Vorlesung "Advanced NMR Spectroscopy"

Lecture Advanced NMR Spectroscopy                          TUMonline

Vorlesung, 3 SWS / 5 ECTS; Chemie (M.Sc.): Schwerpunkt OC (Wahlpflicht), alle HF/NF (Wahlveranstaltung)

Lecturer: G. Gemmecker      Language: English

Time:   Thursday, 12.15 h, seminar room CH26410; start Oct. 19th, 2023
            scripts, tutorials and also last years lectures will be available in Moodle for self-learning

Examination:    written exam (February 2024), please register in TUMonline!

Content:   2D NMR spectroscopy

  • Basic principles of NMR spectroscopy
  • Product operator formalism, principles of 2D NMR
  • 2D pulse sequences for studying structure and conformation of molecules
  • Nuclear Overhauser effect
  • Homo- / heteronuclear NMR

Requirements:  

  • basic NMR knowledge (1D spectra, chemical shifts, J couplings), e.g. from "Grundlagen der analytischen Chemie"

Scripts, homework & other material:  

  • script, exercises etc. are available via Moodle or from below
  • videos from last years lectures are also available (cf. Panopto window in Moddle, file names are refering to the chapters in the script)

 

Additional material (will be added during the course):

 Scripts    Tutorials /
 "Homework"
 Solutions NMR spectra to play with
         
       

 COSYDF (tar archive) 
 COSYDF (PDF file)

 CsA-1H,13C-HSQC (tar file) 
 CsA-1H,13C-HSQC (PDF file)

 CsA-1H,13C-HMBC (tar file) 
 CsA-1H,13C-HMBC (PDF file)

 1H,13C-HSQC (tar archive, 3 MB) - process yourself!
 1H,13C-HSQC (PDF file)

 1H,13C-HMBC (tar archive, 22 MB)  - process yourself!
 1H,13C-HMBC (PDF file)

         
                   

 NEW:   Spindrops

visualization program for NMR
 - try it out!

 

 Workspace files for import into SpinDrops:

 W.1.1_effect_of_rf_field

 W.2.5_chemical_shift

 W.2.6.1_effect_of_pulses_1

 W.2.6.2_effect_of_pulses_2

 W.2.6.3_effect_of_pulses_3

 W.2.7_scalar_coupling

 W.2.8.1_Ialpha

 W.2.8.2_Ibeta

 W.3.0_COSY_transfer

 W.3.1_phase_cycle_COSY

 W.3.2_phase_cycle_DQF-COSY

 (thankfully provided by A. Greiner)