Publications 2018

Kooshapur H, Choudhury NR, Simon B, Muhlbauer M, Jussupow A, Fernandez N, Jones AN, Dallmann A, Gabel F, Camilloni C, Michlewski G, Caceres JF, Sattler M
Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
(2018) Nat Commun 9, 2479. doi: 10.1038/s41467-018-04871-9

Sutandy FXR, Ebersberger S, Huang L, Busch A, Bach M, Kang HS, Fallmann J, Maticzka D, Backofen R, Stadler PF, Zarnack K, Sattler M, Legewie S, Konig J
In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors.
(2018) Genome Res 28, 699-713. doi: 10.1101/gr.229757.117

Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'Kyek O, Jurjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K
Targeting TRAF6 E3 ligase activity with a small molecule inhibitor combats autoimmunity.
(2018) J Biol Chem. doi: 10.1074/jbc.RA118.002649

Rutz DA, Luo Q, Freiburger L, Madl T, Kaila VRI, Sattler M, Buchner J
A switch point in the molecular chaperone Hsp90 responding to client interaction.
(2018) Nat Commun 9, 1472. doi: 10.1038/s41467-018-03946-x

Ghosh D, Koch U, Hadian K, Sattler M, Tetko IV
Luciferase Advisor: High-Accuracy Model To Flag False Positive Hits in Luciferase HTS Assays.
(2018) J Chem Inf Model 58, 933-942. doi: 10.1021/acs.jcim.7b00574

Asami S, Kallies W, Gunther J, Stavropoulou M, Glaser S, Sattler M
Ultrashort broadband cooperative pulses for multidimensional biomolecular nmr experiments.
(2018) Angew Chem Int Ed Engl   doi: 10.1002/anie.201800220

Colaluca IN, Basile A, Freiburger L, D'Uva V, Disalvatore D, Vecchi M, Confalonieri S, Tosoni D, Cecatiello V, Malabarba MG, Yang C-J, Kainosho M, Sattler M, Mapelli M, Pece S, Di Fiore PP
A numb-mdm2 fuzzy complex reveals an isoform-specific involvement of numb in breast cancer.
(2018) J Cell Biol 217, 745-762.   doi: 10.1083/jcb.201709092

Tomala MD, Magiera-Mularz K, Kubica K, Krzanik S, Zieba B, Musielak B, Pustula M, Popowicz GM, Sattler M, Dubin G, Skalniak L, Holak TA
Identification of small-molecule inhibitors of usp2a.
(2018) Eur J Med Chem 150, 261-267.   doi: 10.1016/j.ejmech.2018.03.009

Supekar S, Papageorgiou AC, Gemmecker G, Peltzer R, Johansson MP, Tripsianes K, Sattler M*, Kaila VRI*
Conformational Selection of Dimethylarginine Recognition by the Survival Motor Neuron Tudor Domain.
(2018) Angew Chem Int Ed Engl  57, 486-490.   doi: 10.1002/anie.201708233