Publications 2016
Mourao A, Bonnal S, Soni K, Warner L, Bordonne R, Valcarcel J, and Sattler M
Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
(2016) Elife 5, e14707. [Pubmed] doi: 10.7554/eLife.14707
Voith von Voithenberg L, Sanchez-Rico C, Kang HS, Madl T, Zanier K, Barth A, Warner LR, Sattler M, and Lamb DC
Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
(2016) Proc Natl Acad Sci U S A 113, E7169-E7175. [Pubmed] doi: 10.1073/pnas.1605873113
Zierer BK, Rubbelke M, Tippel F, Madl T, Schopf FH, Rutz DA, Richter K, Sattler M, and Buchner J
Importance of cycle timing for the function of the molecular chaperone Hsp90.
(2016) Nat Struct Mol Biol 23, 1020-1028. [Pubmed] doi: 10.1038/nsmb.3305
Zheng X, Ramani A, Soni K, Gottardo M, Zheng S, Ming Gooi L, Li W, Feng S, Mariappan A, Wason A, Widlund P, Pozniakovsky A, Poser I, Deng H, Ou G, Riparbelli M, Giuliano C, Hyman AA, Sattler M, Gopalakrishnan J, and Li H
Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length.
(2016) Nat Commun 7, 11874. [Pubmed] doi: 10.1038/ncomms11874
Dallmann A, Beribisky AV, Gnerlich F, Rubbelke M, Schiesser S, Carell T, and Sattler M
Site-Specific Isotope-Labeling of Inosine Phosphoramidites and NMR Analysis of an Inosine-Containing RNA Duplex.
(2016) Chemistry 22, 15350-15359. [Pubmed] doi: 10.1002/chem.201602784
Subramaniam S, Erler A, Fu J, Kranz A, Tang J, Gopalswamy M, Ramakrishnan S, Keller A, Grundmeier G, Muller D, Sattler M, and Stewart AF
DNA annealing by Redbeta is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions.
(2016) Sci Rep 6, 34525. [Pubmed] doi: 10.1038/srep34525
Jagtap PK, Garg D, Kapp TG, Will CL, Demmer O, Luhrmann R, Kessler H, and Sattler M
Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
(2016) J Med Chem 59, 10190-10197. [Pubmed] doi: 10.1021/acs.jmedchem.6b01118
Guaitoli G, Raimondi F, Gilsbach BK, Gomez-Llorente Y, Deyaert E, Renzi F, Li X, Schaffner A, Jagtap PK, Boldt K, von Zweydorf F, Gotthardt K, Lorimer DD, Yue Z, Burgin A, Janjic N, Sattler M, Versees W, Ueffing M, Ubarretxena-Belandia I, Kortholt A, and Gloeckner CJ
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
(2016) Proc Natl Acad Sci U S A 113, E4357-66. [Pubmed] doi: 10.1073/pnas.1523708113
Delaforge E, Milles S, Huang JR, Bouvier D, Jensen MR, Sattler M, Hart DJ, and Blackledge M
Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions.
(2016) Front Mol Biosci 3, 54. [Pubmed] doi: 10.3389/fmolb.2016.00054
Janowski R, Heinz GA, Schlundt A, Wommelsdorf N, Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan M, Niessing D, Heissmeyer V, and Sattler M
Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
(2016) Nat Commun 7, 11032. [Pubmed] doi: 10.1038/ncomms11032
Schlundt A, Niessing D, Heissmeyer V, and Sattler M
RNA recognition by Roquin in posttranscriptional gene regulation.
(2016) Wiley Interdiscip Rev RNA. [Pubmed] doi: 10.1002/wrna.1333
Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, and Lickert H
Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.
(2016) PLoS One 11, e0149477. [Pubmed] doi: 10.1371/journal.pone.0149477
Jung B, Messias AC, Schorpp K, Geerlof A, Schneider G, Saur D, Hadian K, Sattler M, Wanker EE, Hasenoder S, and Lickert H
Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.
(2016) Sci Rep 6, 22540. [Pubmed] doi: 10.1038/srep22540
Carlon A, Ravera E, Hennig J, Parigi G, Sattler M, and Luchinat C
Improved accuracy from joint X-ray and NMR refinement of a protein-RNA complex structure.
(2016) J Am Chem Soc 138, 1601-10 [Pubmed] doi: 10.1021/jacs.5b11598
Feracci M, Foot JN, Grellscheid SN, Danilenko M, Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, and Dominguez C
Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
(2016) Nat Commun 7, 10355. [Pubmed] doi: 10.1038/ncomms10355
Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, and Krappmann D
Inhibition of Canonical NF-kappaB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction.
(2016) Sci Rep 6, 18934. [Pubmed] doi: 10.1038/srep18934
Giannopoulou EA, Emmanouilidis L, Sattler M, Dodt G, and Wilmanns M
Towards the molecular mechanism of the integration of peroxisomal membrane proteins.
(2016) Biochim Biophys Acta 1863, 863-9. [Pubmed] doi: 10.1016/j.bbamcr.2015.09.031
Emmanouilidis L, Gopalswamy M, Passon DM, Wilmanns M, and Sattler M
Structural biology of the import pathways of peroxisomal matrix proteins.
(2016) Biochim Biophys Acta 1863, 804-13. [Pubmed] doi: 10.1016/j.bbamcr.2015.09.034